FN Archimer Export Format PT J TI Impact of Putative Probiotics on Growth, Behavior, and the Gut Microbiome of Farmed Arctic Char (Salvelinus alpinus) BT AF Knobloch, Stephen Skírnisdóttir, Sigurlaug Dubois, Marianne Kolypczuk, Laetitia Leroi, Francoise Leeper, Alexandra Passerini, Delphine Marteinsson, Viggó Þ. AS 1:1;2:1;3:2;4:3;5:3;6:1,4;7:3;8:1,5; FF 1:;2:;3:;4:PDG-RBE-MASAE-LEMMMB;5:PDG-RBE-MASAE-LEMMMB;6:;7:PDG-RBE-MASAE-LEMMMB;8:; C1 Microbiology Research Group, Matís ohf., Reykjavík, Iceland ESBS, University of Strasbourg, Strasbourg, France EM3B Laboratory, BRM, IFREMER, Nantes, France Faculty of Biosciences, Department of Animal and Aquaculture Sciences, Norwegian University of Life Sciences, Ås, Norway Faculty of Food Science and Nutrition, University of Iceland, Reykjavik, Iceland C2 MATIS OHF, ICELAND UNIV STRASBOURG, FRANCE IFREMER, FRANCE UNIV NORWEGIAN LIFE SCI, NORWAY UNIV ICELAND, ICELAND SI NANTES SE PDG-RBE-MASAE-LEMMMB IN WOS Ifremer UPR DOAJ copubli-france copubli-europe copubli-univ-france IF 5.2 TC 4 UR https://archimer.ifremer.fr/doc/00785/89720/95188.pdf https://archimer.ifremer.fr/doc/00785/89720/95189.docx https://archimer.ifremer.fr/doc/00785/89720/95190.xlsx https://archimer.ifremer.fr/doc/00785/89720/95191.xlsx https://archimer.ifremer.fr/doc/00785/89720/95192.xlsx LA English DT Article DE ;probiotics;aquaculture;gut microbiome;salmonid;Mycoplasma;growth;behavior AB Beneficial bacteria promise to promote the health and productivity of farmed fish species. However, the impact on host physiology is largely strain-dependent, and studies on Arctic char (Salvelinus alpinus), a commercially farmed salmonid species, are lacking. In this study, 10 candidate probiotic strains were subjected to in vitro assays, small-scale growth trials, and behavioral analysis with juvenile Arctic char to examine the impact of probiotic supplementation on fish growth, behavior and the gut microbiome. Most strains showed high tolerance to gastric juice and fish bile acid, as well as high auto-aggregation activity, which are important probiotic characteristics. However, they neither markedly altered the core gut microbiome, which was dominated by three bacterial species, nor detectably colonized the gut environment after the 4-week probiotic treatment. Despite a lack of long-term colonization, the presence of the bacterial strains showed either beneficial or detrimental effects on the host through growth rate enhancement or reduction, as well as changes in fish motility under confinement. This study offers insights into the effect of bacterial strains on a salmonid host and highlights three strains, Carnobacterium divergens V41, Pediococcus acidilactici ASG16, and Lactiplantibacillus plantarum ISCAR-07436, for future research into growth promotion of salmonid fish through probiotic supplementation. PY 2022 PD JUN SO Frontiers In Microbiology SN 1664-302X PU Frontiers Media SA VL 13 UT 000835094300001 DI 10.3389/fmicb.2022.912473 ID 89720 ER EF