FN Archimer Export Format
PT J
TI Lizards from warm and declining populations are born with extremely short telomeres
BT 
AF Dupoué, Andreaz
   Blaimont, Pauline
   Angelier, Frédéric
   Ribout, Cécile
   Rozen-Rechels, David
   Richard, Murielle
   Miles, Donald
   de Villemereuil, Pierre
   Rutschmann, Alexis
   Badiane, Arnaud
   Aubret, Fabien
   Lourdais, Olivier
   Meylan, Sandrine
   Cote, Julien
   Clobert, Jean
   Le gallard, Jean-François
AS 1:1;2:2,3;3:4;4:4;5:5;6:6;7:7;8:8;9:9;10:5;11:6,10;12:4;13:5;14:11;15:6;16:5,12;
FF 1:;2:;3:;4:;5:;6:;7:;8:;9:;10:;11:;12:;13:;14:;15:;16:;
C1 Laboratoire des sciences de l’environnement marin, Centre National de la Recherche Scientifique, Universite Bretagne Occidentale, Institut de recherche pour le developpement, Institut Francais de Recherche pour l’Exploitation de la Mer, UMR 6539, Plouzane, 29280, France
   Department of Ecology and Evolutionary Biology, University of California, Santa Cruz, CA 95064, USA
   Department of Biology, Rider University, Lawrenceville, NJ 08648, USA
   Centre d’Etudes Biologiques de Chize, Universite de La Rochelle, CNRS, UMR 7372, Beauvoir sur Niort, 79360, France
   Institut d’ecologie et des sciences de l’environnement de Paris, CNRS, UMR 7618, Sorbonne Universite, Paris, 75005, France
   Station d’Ecologie Theorique et Experimentale de Moulis, CNRS, UMR 5321, Saint Girons, 09200, France
   Department of Biological Sciences, Ohio University, Athens, OH 45701, Greece
   Institut de Systematique,Evolution, Biodiversite, CNRS, Museum national d’Histoire naturelle, Sorbonne Universite, Ecole Pratique des Hautes Etudes and Universite des Antilles, UMR 72
   School of Biological Sciences, University of Auckland, Auckland, 1142, New Zealand
   School of Agricultural, Environmental and Veterinary Sciences, Faculty of Science and Health, Charles Sturt University, Port Macquarie NSW 2444, Australia
   Laboratoire Evolution et Diversite Biologique, CNRS, UMR 5174, Toulouse, 31077, France
   Centre de recherche en ecologie experimentale et predictive-Ecotron IleDeFrance, CNRS, Ecole Normale Superieure, UMS 3194, Saint-Pierre-les-Nemours, 77140, France
C2 Laboratoire des sciences de l’environnement marin, Centre National de la Recherche Scientifique, Universite Bretagne Occidentale, Institut de recherche pour le developpement, Institut Francais de Recherche pour l’Exploitation de la Mer, UMR 6539, Plouzane, 29280, France
   UNIV CALIF SANTA CRUZ, USA
   UNIV RIDER, USA
   UNIV LA ROCHELLE, FRANCE
   UNIV SORBONNE, FRANCE
   CNRS, FRANCE
   UNIV OHIO, GREECE
   MNHN, FRANCE
   UNIV AUCKLAND, NEW ZEALAND
   UNIV CHARLES STURT, AUSTRALIA
   CNRS, FRANCE
   CNRS, FRANCE
IF 11.1
TC 21
UR https://archimer.ifremer.fr/doc/00787/89946/95444.pdf
   https://archimer.ifremer.fr/doc/00787/89946/95445.pdf
LA English
DT Article
DE ;aging;ectotherms;population extinction;telomeres;life-history tradeoffs
AB Aging is the price to pay for acquiring and processing energy through cellular activity and life history productivity. Climate warming can exacerbate the inherent pace of aging, as illustrated by a faster erosion of protective telomere DNA sequences. This biomarker integrates individual pace of life and parental effects through the germline, but whether intra- and intergenerational telomere dynamics underlies population trends remains an open question. Here, we investigated the covariation between life history, telomere length (TL), and extinction risk among three age classes in a cold-adapted ectotherm (Zootoca vivipara) facing warming-induced extirpations in its distribution limits. TL followed the same threshold relationships with population extinction risk at birth, maturity, and adulthood, suggesting intergenerational accumulation of accelerated aging rate in declining populations. In dwindling populations, most neonates inherited already short telomeres, suggesting they were born physiologically old and unlikely to reach recruitment. At adulthood, TL further explained females’ reproductive performance, switching from an index of individual quality in stable populations to a biomarker of reproductive costs in those close to extirpation. We compiled these results to propose the aging loop hypothesis and conceptualize how climate-driven telomere shortening in ectotherms may accumulate across generations and generate tipping points before local extirpation. 
PY 2022
PD AUG
SO Proceedings Of The National Academy Of Sciences Of The United States Of America
SN 0027-8424
PU Proceedings of the National Academy of Sciences
VL 119
IS 33
UT 000891285200008
DI 10.1073/pnas.2201371119
ID 89946
ER

EF