FN Archimer Export Format
PT J
TI The paradoxes hidden behind the Droop model highlighted by a metabolic approach
BT 
AF Baroukh, Caroline
   MAIRET, Francis
   Bernard, Olivier
AS 1:1;2:2;3:3;
FF 1:;2:PDG-ODE-PHYTOX-PHYSALG;3:;
C1 LIPME, INRA, CNRS, Université de Toulouse, France
   Ifremer, PHYTOX, Laboratoire PHYSALG, France
   Biocore, INRIA, Université Côte d’Azur, France
C2 UNIV TOULOUSE, FRANCE
   IFREMER, FRANCE
   INRIA, FRANCE
SI NANTES
SE PDG-ODE-PHYTOX-PHYSALG
IN WOS Ifremer UPR
   DOAJ
   copubli-france
   copubli-univ-france
IF 5.6
TC 2
UR https://archimer.ifremer.fr/doc/00788/89995/95551.pdf
   https://archimer.ifremer.fr/doc/00788/89995/95552.xlsx
   https://archimer.ifremer.fr/doc/00788/89995/95553.zip
   https://archimer.ifremer.fr/doc/00788/89995/95554.tiff
   https://archimer.ifremer.fr/doc/00788/89995/95555.eps
LA English
DT Article
DE ;metabolic network;microalgae;nitrogen stress;excretion;Tisochrysis lutea
AB We propose metabolic models for the haptophyte microalgae Tisochyrisis lutea with different possible organic carbon excretion mechanisms. These models - based on the DRUM (Dynamic Reduction of Unbalanced Metabolism) methodology - are calibrated with an experiment of nitrogen starvation under day/night cycles, and then validated with nitrogen-limited chemostat culture under continuous light. We show that models including exopolysaccharide excretion offer a better prediction capability. It also gives an alternative mechanistic interpretation to the Droop model for nitrogen limitation, which can be understood as an accumulation of carbon storage during nitrogen stress, rather than the common belief of a nitrogen pool driving growth. Excretion of organic carbon limits its accumulation, which leads to a maximal C/N ratio (corresponding to the minimum Droop N/C quota). Although others phenomena - including metabolic regulations and dissipation of energy - are possibly at stake, excretion appears as a key component in our metabolic model, that we propose to include in the Droop model. 
PY 2022
PD AUG
SO Frontiers In Plant Science
SN 1664-462X
PU Frontiers Media
VL 13
UT 000872546100001
DI 10.3389/fpls.2022.941230
ID 89995
ER

EF