FN Archimer Export Format PT J TI Optimal control of microbial production in the chemostat BT AF Bayen, Terence Cazenave-Lacroutz, Henri Coville, Jérôme Mairet, Francis AS 1:1;2:1;3:2;4:3; FF 1:;2:;3:;4:PDG-ODE-PHYTOX-PHYSALG; C1 Avignon Université, Laboratoire de Mathématiques d'Avignon (EA 2151) F-84018 France UR 546 Biostatistique et Processus Spatiaux, INRAE, Domaine St Paul Site Agroparc, F-84000 Avignon, France Ifremer, Physiology and Biotechnology of Algae laboratory, rue de l'Ile d'Yeu, 44311 Nantes, France C2 UNIV AVIGNON, FRANCE INRAE, FRANCE IFREMER, FRANCE SI NANTES SE PDG-ODE-PHYTOX-PHYSALG IN WOS Ifremer UPR copubli-france copubli-p187 copubli-univ-france TC 0 UR https://archimer.ifremer.fr/doc/00794/90599/96169.pdf LA English DT Article DE ;Optimal control;Pontryagin maximum principle;singular arcs;chemostat system;dynamical system;global stability AB In this work, we study the problem of maximizing microbial production within a continuous stirred-tank reactor with n ≥ 1 species and one substrate. The interaction between species is described by the chemostat system including a mutation factor. The optimization problem falls into an optimal control problem of Lagrange type in which the control parameter is the dilution rate of the reactor. Thanks to the Pontryagin Maximum Principle, we obtain necessary conditions on optimal controls that involve a singular arc. These computations are highlighted thanks to numerical simulations via a direct method. We also study the related optimization problem at steady-state which provides an insight into optimal solutions of the optimal control problem in terms of turnpike phenomenon.   PY 2022 SO Ifac Papersonline SN 2405-8963 PU Elsevier BV VL 55 IS 16 UT 000855235100035 BP 208 EP 213 DI 10.1016/j.ifacol.2022.09.025 ID 90599 ER EF