FN Archimer Export Format
PT J
TI Thermal imprinting during embryogenesis modifies skin repair in juvenile European sea bass (Dicentrarchus labrax)
BT 
AF Mateus, Ana Patrícia
   Costa, Rita A.
   Sadoul, Bastien
   Bégout, Marie-Laure
   Cousin, Xavier
   Canario, Adelino VM.
   Power, Deborah M.
AS 1:1,2;2:1;3:3,4;4:3;5:6;6:1,5;7:1,5;
FF 1:;2:;3:PDG-RBE-MARBEC-LAAAS;4:PDG-RBE-MARBEC-LSEA;5:;6:;7:;
C1 Centro de Ciências do Mar (CCMAR), Comparative Endocrinology and Integrative Biology, Universidade do Algarve, Campus de Gambelas, 8005-139, Faro, Portugal
   Escola Superior de Saúde, Universidade do Algarve, Campus de Gambelas, 8005-139, Faro, Portugal
   MARBEC, Univ Montpellier, CNRS, Ifremer, IRD, INRAE, 34250, Palavas-Les-Flots, France
   DECOD, Ecosystem Dynamics and Sustainability, Institut Agro, Ifremer, INRAE, Rennes, France
   International Institution of Marine Science, Shanghai Ocean University, Shanghai, China
   MARBEC, Univ Montpellier, CNRS, Ifremer, IRD, INRAE, 34250, Palavas-Les-Flots, France
C2 UNIV ALGARVE CCMAR, PORTUGAL
   UNIV ALGARVE, PORTUGAL
   IFREMER, FRANCE
   INST AGRO RENNES-ANGERS, FRANCE
   UNIV SHANGHAI OCEAN, CHINA
   INRAE, FRANCE
SI PALAVAS
SE PDG-RBE-MARBEC-LAAAS
   PDG-RBE-MARBEC-LSEA
UM MARBEC
   DECOD
IN WOS Ifremer UMR
   WOS Cotutelle UMR
   copubli-france
   copubli-p187
   copubli-europe
   copubli-int-hors-europe
   copubli-sud
IF 4.7
TC 1
UR https://archimer.ifremer.fr/doc/00824/93568/100293.pdf
   https://archimer.ifremer.fr/doc/00824/93568/100294.docx
LA English
DT Article
DE ;Wound healing;Phenotypic plasticity;Reepithelialization;Antioxidant defence;Melanomacrophages
AB Fish skin is a multifunctional tissue that develops during embryogenesis, a developmental stage highly susceptible to epigenetic marks. In this study, the impact of egg incubation temperature on the regeneration of a cutaneous wound caused by scale removal in juvenile European sea bass was evaluated. Sea bass eggs were incubated at 11, 13.5 and 16 °C until hatching and then were reared at a common temperature until 9 months when the skin was damaged and sampled at 0, 1 and 3 days after scale removal and compared to the intact skin from the other flank. Skin damage elicited an immediate significant (p < 0.001) up-regulation of pcna in fish from eggs incubated at higher temperatures. In fish from eggs incubated at 11 °C there was a significant (p < 0.001) up-regulation of krt2 compared to fish from higher thermal backgrounds 1 day after skin damage. Damaged epidermis was regenerated after 3 days in all fish irrespective of the thermal background, but in fish from eggs incubated at 11 °C the epidermis was significantly (p < 0.01) thinner compared to other groups, had less goblet cells and less melanomacrophages. The thickness of the dermis increased during regeneration of wounded skin irrespective of the thermal background and by 3 days was significantly (p < 0.01) thicker than the dermis from the intact flank. The expression of genes for ECM remodelling (mmp9, colXα, col1α1, sparc, and angptl2b) and innate immunity (lyg1, lalba, sod1, csf-1r and pparγ) changed during regeneration but were not affected by egg thermal regime. Overall, the results indicate that thermal imprinting of eggs modifies the damage-repair response in juvenile sea bass skin. 
PY 2023
PD MAR
SO Fish & Shellfish Immunology
SN 1050-4648
PU Elsevier BV
VL 134
UT 000952266000001
DI 10.1016/j.fsi.2023.108647
ID 93568
ER

EF