FN Archimer Export Format
PT J
TI Effect of Early Peptide Diets on Zebrafish Skeletal Development
BT 
AF PRINTZI, Aliki
   Koumoundouros, George
   Fournier, Vincent
   Madec, Lauriane
   Zambonino-Infante, Jose-Luis
   Mazurais, David
AS 1:1,2;2:1;3:3;4:2;5:2;6:2;
FF 1:PDG-RBE-PHYTNESS;2:;3:;4:PDG-RBE-PHYTNESS;5:PDG-RBE-PHYTNESS;6:PDG-RBE-PHYTNESS;
C1 Biology Department, University of Crete, 70013 Crete, Greece
   IFREMER, University of Brest, CNRS, IRD, LEMAR, F-29280 Plouzané, France
   DianaAqua, Symrise Group, 56250 Elven, France
C2 UNIV CRETE, GREECE
   IFREMER, FRANCE
   DIANAAQUA, FRANCE
SI BREST
SE PDG-RBE-PHYTNESS
UM LEMAR
IN WOS Ifremer UMR
   DOAJ
   copubli-france
   copubli-europe
IF 5.5
TC 3
UR https://archimer.ifremer.fr/doc/00832/94438/101751.pdf
   https://archimer.ifremer.fr/doc/00832/94438/101752.zip
LA English
DT Article
DE ;nutrition;peptides;skeletal development;haemal lordosis;zebrafish;gene markers
AB Incorporation of dietary peptides has been correlated with decreased presence of skeletal abnormalities in marine larvae. In an attempt to clarify the effect of smaller protein fractions on fish larval and post-larval skeleton, we designed three isoenergetic diets with partial substitution of their protein content with 0% (C), 6% (P6) and 12% (P12) shrimp di- and tripeptides. Experimental diets were tested in zebrafish under two regimes, with inclusion (ADF-Artemia and dry feed) or lack (DF-dry feed only) of live food. Results at the end of metamorphosis highlight the beneficial effect of P12 on growth, survival and early skeletal quality when dry diets are provided from first feeding (DF). Exclusive feeding with P12 also increased the musculoskeletal resistance of the post-larval skeleton against the swimming challenge test (SCT). On the contrary, Artemia inclusion (ADF) overruled any peptide effect in total fish performance. Given the unknown species’ larval nutrient requirements, a 12% dietary peptide incorporation is proposed for successful rearing without live food. A potential nutritional control of the larval and post-larval skeletal development even in aquaculture species is suggested. Limitations of the current molecular analysis are discussed to enable the future identification of the peptide-driven regulatory pathways. 
PY 2023
PD APR
SO Biomolecules
SN 2218-273X
PU MDPI AG
VL 13
IS 4
UT 000979214800001
DI 10.3390/biom13040659
ID 94438
ER

EF