FN Archimer Export Format
PT J
TI Phenotype stability and dynamics of transposable elements in a strain of the microalga Tisochrysis lutea with improved lipid traits
BT 
AF Berthelier, Jérémy
   Saint-Jean, Bruno
   Casse, Nathalie
   Bougaran, Gael
   Carrier, Gregory
AS 1:1,2,3;2:4;3:2;4:5;5:4;
FF 1:PDG-RBE-BRM-LPBA;2:PDG-ODE-PHYTOX-GENALG;3:;4:PDG-ODE-PHYTOX-PHYSALG;5:PDG-ODE-PHYTOX-GENALG;
C1 Laboratory PBA, Ifremer, Nantes, France
   Laboratory of Biology of Organisms Stress Health Environment (BiOSSE), Le Mans University, Le Mans, France
   Plant Epigenetics Unit, Okinawa Institute of Science and Technology Graduate University, Onna, Okinawa, Japan
   Laboratory PHYTOX GENALG, Ifremer, Nantes, France
   Laboratory PHYTOX PHYSALG, Ifremer, Nantes, France
C2 IFREMER, FRANCE
   UNIV LE MANS, FRANCE
   UNIV OKINAWA, JAPAN
   IFREMER, FRANCE
   IFREMER, FRANCE
SI NANTES
SE PDG-RBE-BRM-LPBA
   PDG-ODE-PHYTOX-GENALG
   PDG-ODE-PHYTOX-PHYSALG
IN WOS Ifremer UPR
   DOAJ
   copubli-france
   copubli-univ-france
   copubli-int-hors-europe
IF 3.7
TC 0
UR https://archimer.ifremer.fr/doc/00835/94690/102104.pdf
   https://archimer.ifremer.fr/doc/00835/94690/102105.tif
   https://archimer.ifremer.fr/doc/00835/94690/102106.tif
   https://archimer.ifremer.fr/doc/00835/94690/102107.tif
   https://archimer.ifremer.fr/doc/00835/94690/102108.tif
   https://archimer.ifremer.fr/doc/00835/94690/102109.tif
   https://archimer.ifremer.fr/doc/00835/94690/102110.xlsx
   https://archimer.ifremer.fr/doc/00835/94690/102111.xlsx
   https://archimer.ifremer.fr/doc/00835/94690/102112.pdf
   https://archimer.ifremer.fr/doc/00835/94690/102113.xlsx
   https://archimer.ifremer.fr/doc/00835/94690/102114.pdf
   https://archimer.ifremer.fr/doc/00835/94690/102115.xlsx
   https://archimer.ifremer.fr/doc/00835/94690/102116.pdf
   https://archimer.ifremer.fr/doc/00835/94690/102117.xlsx
LA English
DT Article
AB Microalgal domestication is an expanding research field that aims to multiply and accelerate the potential of microalgae for various biotechnological purposes. We investigated the stability of improved lipid traits and genetic changes of a domesticated strain of the haptophyte Tisochrysis lutea, TisoS2M2, previously obtained by a mutation-selection improvement program. After 7 years of maintenance, TisoS2M2 still displayed improved lipid traits compared with the native strain, demonstrating that a mutation-selection improvement program is suitable for obtaining a domesticated strain with stable, improved phenotype over time. We identified specific genetic variations between the native and domesticated strains and focused on the dynamics of transposable elements (TEs). DNA transposons mainly caused specific TE indels of the domesticated strain TisoS2M2, and some specific TE indels may have impacted genes associated to the neutral lipid pathway. We revealed transposition events for TEs in T. lutea and discussed on the potential role of the improvement program on their activity. 
PY 2023
PD APR
SO Plos One
SN 1932-6203
PU Public Library of Science (PLoS)
VL 18
IS 4
UT 000990748100082
DI 10.1371/journal.pone.0284656
ID 94690
ER

EF