FN Archimer Export Format
PT J
TI A core of functional complementary bacteria infects oysters in Pacific Oyster Mortality Syndrome
BT 
AF Clerissi, Camille
   Luo, Xing
   Lucasson, Aude
   Mortaza, Shogofa
   de Lorgeril, Julien
   Toulza, Eve
   Petton, Bruno
   Escoubas, Jean-Michel
   Dégremont, Lionel
   Gueguen, Yannick
   DESTOUMIEUX GARZON, Delphine
   Jacq, Annick
   Mitta, Guillaume
AS 1:1,2,3;2:4;3:2;4:4;5:1,5;6:2;7:6;8:2;9:7;10:1,8;11:10;12:4;13:9,10;
FF 1:PDG-RBE-IHPE;2:;3:;4:;5:PDG-RBE-LEADNC;6:;7:PDG-RBE-PHYTNESS;8:;9:PDG-RBE-ASIM;10:PDG-ODE-LITTORAL-LERLR;11:;12:;13:PDG-RBE-RMPF;
C1 IHPE, Université de Montpellier, CNRS, Ifremer, Université de Perpignan Via Domitia, Place E. Bataillon, CC080, 34095, Montpellier, France
   Université de Perpignan Via Domitia, 58 Avenue Paul Alduy, 66860, Perpignan, France
   CNRS, UAR 3278 CRIOBE, CRIOBE, EPHE, Université PSL, UPVD, 52 Avenue Paul Alduy, 66860, Perpignan Cedex, France
   CEA, CNRS, Institute for Integrative Biology of the Cell (I2BC), Université Paris-Saclay, 91198, Gif-Sur-Yvette, France
   Ifremer, IRD, Univ Nouvelle-Calédonie, Univ La Réunion, ENTROPIE, 98800, Nouméa, Nouvelle-Calédonie, France
   Ifremer, LEMAR UMR 6539, UBO, CNRS, IRD, Ifremer, 11 Presqu’île du Vivier, 29840, Argenton-en-Landunvez, France
   Ifremer, SG2M, LGPMM, Avenue du Mus de Loup, 17930, La Tremblade, France
   CNRS, Ifremer, IRD, MARBEC, Univ Montpellier, Sète, France
   Ifremer, IRD, ILM, Université de Polynésie Française, UMR 241, Vairao, French Polynesia
   IHPE, Université de Montpellier, CNRS, Ifremer, Université de Perpignan Via Domitia, Place E. Bataillon, CC080, 34095, Montpellier, France
C2 IFREMER, FRANCE
   UNIV PERPIGNAN, FRANCE
   CNRS, FRANCE
   CEA, FRANCE
   IFREMER, FRANCE
   IFREMER, FRANCE
   IFREMER, FRANCE
   IFREMER, FRANCE
   IFREMER, FRANCE
   CNRS, FRANCE
SI MONTPELLIER
   SAINT VINCENT
   BREST
   LA TREMBLADE
   SETE
   TAHITI
SE PDG-RBE-IHPE
   PDG-RBE-LEADNC
   PDG-RBE-PHYTNESS
   PDG-RBE-ASIM
   PDG-ODE-LITTORAL-LERLR
   PDG-RBE-RMPF
UM LEMAR
   MARBEC
   IHPE
   EIO
   ENTROPIE
IN WOS Ifremer UPR
   WOS Ifremer UMR
   WOS Cotutelle UMR
   DOAJ
   copubli-france
   copubli-univ-france
TC 4
UR https://archimer.ifremer.fr/doc/00835/94708/102173.pdf
   https://archimer.ifremer.fr/doc/00835/94708/102174.tiff
   https://archimer.ifremer.fr/doc/00835/94708/102175.tiff
   https://archimer.ifremer.fr/doc/00835/94708/102176.tiff
   https://archimer.ifremer.fr/doc/00835/94708/102177.tiff
   https://archimer.ifremer.fr/doc/00835/94708/102178.tiff
   https://archimer.ifremer.fr/doc/00835/94708/102179.tiff
   https://archimer.ifremer.fr/doc/00835/94708/102180.tiff
   https://archimer.ifremer.fr/doc/00835/94708/102181.tiff
   https://archimer.ifremer.fr/doc/00835/94708/102182.xlsx
   https://archimer.ifremer.fr/doc/00835/94708/102183.xlsx
   https://archimer.ifremer.fr/doc/00835/94708/102184.xlsx
   https://archimer.ifremer.fr/doc/00835/94708/102185.xlsx
   https://archimer.ifremer.fr/doc/00835/94708/102186.xlsx
   https://archimer.ifremer.fr/doc/00835/94708/102187.xlsx
   https://archimer.ifremer.fr/doc/00835/94708/102188.xlsx
   https://archimer.ifremer.fr/doc/00835/94708/102189.xlsx
   https://archimer.ifremer.fr/doc/00835/94708/102190.xlsx
LA English
DT Article
DE ;Metabarcoding;Metatranscriptomics;Pathobiota;Metabolism;Resource partitioning
AB Background The Pacific oyster Crassostrea gigas is one of the main cultivated invertebrate species worldwide. Since 2008, oyster juveniles have been confronted with a lethal syndrome known as the Pacific Oyster Mortality Syndrome (POMS). POMS is a polymicrobial disease initiated by a primary infection with the herpesvirus OsHV-1 µVar that creates an oyster immunocompromised state and evolves towards a secondary fatal bacteremia. Results In the present article, we describe the implementation of an unprecedented combination of metabarcoding and metatranscriptomic approaches to show that the sequence of events in POMS pathogenesis is conserved across infectious environments. We also identified a core bacterial consortium which, together with OsHV-1 µVar, forms the POMS pathobiota. This bacterial consortium is characterized by high transcriptional activities and complementary metabolic functions to exploit host’s resources. A significant metabolic specificity was highlighted at the bacterial genus level, suggesting low competition for nutrients between members of the core bacteria. Conclusions Lack of metabolic competition between the core bacteria might favor complementary colonization of host tissues and contribute to the conservation of the POMS pathobiota across distinct infectious environments. 
PY 2023
PD MAY
SO Animal Microbiome
SN 2524-4671
PU Springer Science and Business Media LLC
VL 5
IS 1
UT 000980952700001
DI 10.1186/s42523-023-00246-8
ID 94708
ER

EF