FN Archimer Export Format
PT J
TI Embryogenesis of an aquaculture fish (Dicentrarchus labrax) under simulated altered gravity
BT 
AF PRZYBYLA, Cyrille
   Bonneffoy, Julie
   Paounov, Rapphaelle
   Debiol, Amelys
   DUTTO, Gilbert
   MANSUY, Emmanuel
   LALLEMENT, Stephane
   Coste, Florence
   GEFFROY, Benjamin
   Frippiat, Jean Pol
AS 1:1;2:2;3:3;4:3;5:1;6:1;7:1;8:2;9:1;10:2;
FF 1:PDG-RBE-MARBEC-LAAAS;2:;3:;4:;5:PDG-RBE-MARBEC-LSEA;6:PDG-RBE-MARBEC-LSEA;7:PDG-RBE-MARBEC-LSEA;8:;9:PDG-RBE-MARBEC-LAAAS;10:;
C1 MARBEC, Université de Montpellier, CNRS, IFREMER, IRD, France
   Université de Lorraine, SIMPA, Nancy, France
   MARBEC, Université de Montpellier, CNRS, IFREMER, IRD, France
C2 IFREMER, FRANCE
   UNIV LORRAINE, FRANCE
   UNIV MONTPELLIER, FRANCE
SI PALAVAS
SE PDG-RBE-MARBEC-LAAAS
   PDG-RBE-MARBEC-LSEA
UM MARBEC
IN WOS Ifremer UMR
   WOS Cotutelle UMR
   DOAJ
   copubli-france
   copubli-univ-france
TC 0
UR https://archimer.ifremer.fr/doc/00856/96749/105296.pdf
LA English
DT Article
DE ;Complement component 3;European seabass;glucocorticoid receptors;heat shock protein 90;hypergravity;interleukin-1 beta;microgravity;space aquaculture
AB Food production and balanced nutrition will be a key challenge for residents of a future base on the Moon or Mars. As a complement to photosynthetic organisms, space aquaculture could provide the range of amino acids required to maintain health. This would rely on shipping fertilized aquaculture fish eggs to the Moon. To determine the feasibility of this, this study sought to test the influence of the conditions of a lunar mission—such as hypergravity during rocket launch and microgravity during the journey—on fish embryos and young larvae. To analyze the potential effects of these gravity changes on the early developmental stages of fish, we conducted two experiments to expose them to: i) 10 min of simulated hypergravity at 5 g (launch duration) and ii) 39 h of simulated microgravity using a random positioning machine. Both experiments used European sea bass (Dicentrarchus labrax) as a model. We analyzed egg oxygen consumption and hatching rates, as well as the expression of genes related to stress and immunity. The results indicated that neither of these altered gravity conditions affected the hatching rate. Simulated microgravity did not impact fish embryo oxygen consumption and appeared to induce faster embryonic development, as the eggs hatched earlier than expected. Levels of glucocorticoid receptors (GR1 and GR2) and heat shock proteins (Hsp90) were not impacted. Only the levels of complement component protein 3 (C3) were significantly higher in simulated microgravity, while interleukin-1β (IL-1β) transcripts were significantly lower in the hypergravity group, compared to controls. This shows that proteins involved in the innate immune system are expressed under altered gravity. Although further experiments are needed, these results suggest that the European sea bass is a promising candidate for space aquaculture. 
PY 2023
PD OCT
SO Frontiers In Space Technologies
SN 2673-5075
PU Frontiers Media
VL 4
UT 001189734300001
DI 10.3389/frspt.2023.1240251
ID 96749
ER

EF