FN Archimer Export Format
PT J
TI Alginate microgels encapsulation strategy of silver nanoparticles active against Candida albicans
BT 
AF Marquis, Mélanie
   Musino, Dafne
   Gemin, Valentin
   Kolypczuk, Laetitia
   Passerini, Delphine
   Capron, Isabelle
AS 1:1,2;2:1;3:1;4:3;5:3;6:1;
FF 1:;2:;3:;4:PDG-RBE-MASAE-LEMMMB;5:PDG-RBE-MASAE-LEMMMB;6:;
C1 INRAE, UR1268 Biopolymers Interactions and Assemblies, 44300 Nantes, France
   Oniris, INRAE, UMR0703 Physiopathologie Animale et BioThérapie du muscle et du système nerveux, 44307 Nantes, France
   Ifremer, MASAE Microbiologie Aliment Santé Environnement, 44000 Nantes, France
C2 INRAE, FRANCE
   ONIRIS, FRANCE
   IFREMER, FRANCE
SI NANTES
SE PDG-RBE-MASAE-LEMMMB
IN WOS Ifremer UPR
   DOAJ
   copubli-france
   copubli-p187
TC 0
UR https://archimer.ifremer.fr/doc/00867/97932/107054.pdf
   https://archimer.ifremer.fr/doc/00867/97932/107055.docx
LA English
DT Article
DE ;Cellulose nanocrystal (CNC);Chitin nanocrystal (ChiNC);Hybrid;Microfluidic;Hydrogel;Antimicrobial activities
AB Nanoparticles (NPs), offering high specific surface, are considered as the best potential anti-microbial agents for a wide range of medical nanotechnology. Among them, silver NPs (AgNPs) allow high biocidal activity. A design of ecological capsules is proposed where AgNPs of 22 nm in diameter are grafted on the surface of biobased nanocrystals obtained from cellulose (CNC) and chitin (ChiNC). These silver nanohybrids are dispersed in calcium-alginate microgels of 45–50 µm in diameter using microfluidic tools. Such double level of immobilization of AgNPs leads to highly stable carriers, prolongs shelf life and raises bioactivity, with a precise control of well dispersed AgNPs as determined by scanning transmission electron microscopy, UV-Vis spectroscopy and atomic absorption spectroscopy. Preliminary tests for antimicrobial activities of these new microgels have shown a significant inhibitory effect on Candida albicans, the most common fungal pathogen, responsible for thrush and vaginal yeast infections, for very low levels of silver. 
PY 2023
PD DEC
SO Carbohydrate Polymer Technologies And Applications
SN 2666-8939
PU Elsevier BV
VL 6
UT 001137503000001
DI 10.1016/j.carpta.2023.100405
ID 97932
ER

EF