A comparison of chlorophyll data from SeaWiFS imagery and modeling results from a 3D hydrodynamical model was performed over the northwestern Mediterranean for the entire year of 2001. The study aims at investigating the information content brought by satellite-derived chlorophyll concentration ([Chl]) maps concerning surface dynamics in coastal zone. The study is mainly focused on the Gulf of Lions (GoL) and its outer region, which are mainly influenced by the Rh ne River, local winds and the Northern Current (NC) flowing from the East along the continental slope. The physical hydrodynamical model was continuously run and 40 SeaWiFS images, presenting a significant coverage of the studied area, were selected. The comparison between [ Chl] and sea surface salinity (SSS) fields on a pixel basis showed no definite correlation trends. Three reasons are given in discussion for that result. However, the comparison emphasized areas close to the coasts which were under the influence of different inputs not considered in the model and also of upwellings. A qualitative analysis of the data performed out of these regions exhibited significant similarities between [ Chl] and SSS features. The signature of the Rh ne ROFI ( Region of Fresh Water Influence) and, in some cases, of the NC, was evidenced on [ Chl] maps. We found that the intensity of this signature is seasonally modulated, e. g., it is low in open sea during the summer, oligotrophic, season. In addition, the signature of the Rh ne ROFI in the western part of the GoL can be only partial due to local chlorophyll deficits. We conclude that, for the regional case studied, chlorophyll imagery can be used as a tracer of surface dynamics through surface salinity but with limitations, especially near the coasts.