New short peptaibols from a marine Trichoderma strain
| Type | Article | ||||||||
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| Date | 2006-03 | ||||||||
| Language | English | ||||||||
| Author(s) | Mohamed Benkada M1, Montagu M1, Biard J1, Mondeguer Florence 2, Verite P3, Dalgalarrondo M4, Bissett J5, Pouchus Y1 |
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| Affiliation(s) | 1 : Univ Nantes, Grp SMAB, EA 2160, Fac Pharm, F-44035 Nantes 1, France. 2 : IFREMER, Ctr Nantes, DEL PN, Nantes 3, France. 3 : UFR Mixte Med Pharm, Lab Chim Analyt, F-76183 Rouen, France. 4 : INRA, LEIMA, F-44316 Nantes 3, France. 5 : Agr & Agri Food Canada, ECORC, Ottawa, ON K1A 0C6, Canada. |
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| Source | Rapid communications in mass spectrometry (0951-4198) (John Wiley Interscience), 2006-03 , Vol. 20 , N. 8 , P. 1176-1180 | ||||||||
| DOI | 10.1002/rcm.2430 | ||||||||
| WOS© Times Cited | 43 | ||||||||
| Keyword(s) | Trichoderma longibrachiatum, Marine fungi, Marine products, Electrospray ionisation multiple stage mass spectrometry ion trap (ESI MSn IT), Short peptaibols | ||||||||
| Abstract | The production of peptaibols by a marine-related Trichoderma longibrachiatum strain was studied using electrospray ionisation multiple-stage ion trap mass spectrometry (ESI-MSn-IT) and gas chromatography/electron impact mass spectrometry (GC/EI-MS). Two major groups of peptaibols were identified, those with long sequences (20 amino acids) and others with short sequences (11 amino acids). This paper describes the methodology used to establish the sequences of short peptaibols in a mixture without previous individual separation. Nine peptaibols were identified. Among them, eight are new, namely as trichobrachin A I-IV (Aib(9)-Pro(10) sequence) and as trichobrachin B I-IV (Val(9)-Pro(10) sequence). Original Pro(6)-Val(7) and Val(9)-Pro(10) sequences have to be noted. | ||||||||
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