Viral gametocytic hypertrophy of Crassostrea gigas in France: from occasional records to disease emergence?

Type Article
Date 2006-06
Language English
Author(s) Garcia Celine1, Robert Maeva1, Arzul IsabelleORCID1, Chollet Bruno, Joly Jean-Pierre1, Miossec Laurence1, Comtet Thierry2, Berthe Franck1, 3
Affiliation(s) 1 : IFREMER, Lab Genet & Pathol, F-17390 La Tremblade, France.
2 : CNRS 7127, Equipe Ecol Benthique, Biol Stn, F-29682 Roscoff, France.
3 : Univ Prince Edward Isl, Atlantic Vet Coll, Dept Pathol & Microbiol, Charlottetown, PE C1A 4P3, Canada.
Source Diseases of aquatic organisms (0177-5103) (Inter-Research), 2006-06 , Vol. 70 , N. 3 , P. 193-199
WOS© Times Cited 21
Keyword(s) Polyomaviridae, Papillomaviridae, Gonad, Viral garnetocytic hypertrophy, Pacific oyster, Crassostrea gigas
Abstract Viral gametocytic hypertrophy was reported for the first time in 2001 in Pacific oyster Crassostrea gigas in France. Since this date, the number of reported cases and the distribution area have increased every year; however, the cases are not associated with macroscopic signs or increased mortality rates. Both male and female gametes were hypertrophied and basophilic inclusions were observed in gamete nuclei, Transmission electron microscopy revealed the presence of viral particles in these intranuclear basophilic inclusions. These particles had characteristics similar to those of the Papillomaviridae and Polyomaviridae families: they were small, non-enveloped, icosahedral, and 44 to 56 nm in diameter, The viral particles were found in male, female and hermaphrodite oysters and no significant difference in viral infection was observed between those groups. The frequency of detection and the intensity of infection were low and no host defence reaction was recognised, suggesting that the viral particles had a weak impact on C. gigas. The viral particles described in the present study seem to be similar to these described in C. virginica in the USA and Canada and in C. gigas in Korea, but further studies are required to confirm their identity. The issue of a possible emergence of this infection is discussed.
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Garcia Celine, Robert Maeva, Arzul Isabelle, Chollet Bruno, Joly Jean-Pierre, Miossec Laurence, Comtet Thierry, Berthe Franck (2006). Viral gametocytic hypertrophy of Crassostrea gigas in France: from occasional records to disease emergence? Diseases of aquatic organisms, 70(3), 193-199. Open Access version :