Evolutionary history and genetic parallelism affect correlated responses to evolution

Type Article
Date 2013-06
Language English
Author(s) Le Gac MickaelORCID1, 2, Cooper Tim F.3, Cruveiller Stephane4, 5, Edigue Claudine M.4, 5, Schneider Dominique1, 2
Affiliation(s) 1 : Univ Grenoble 1, Lab Adaptat & Pathogenie Microorganismes, F-38042 Grenoble 9, France.
2 : CNRS, UMR 5163, F-38042 Grenoble 9, France.
3 : Univ Houston, Dept Biol & Biochem, Houston, TX 77204 USA.
4 : CNRS, UMR 8030, F-91057 Evry, France.
5 : CEA, DSV, IG, Genoscope LABGeM, F-91057 Evry, France.
Source Molecular Ecology (0962-1083) (Wiley-blackwell), 2013-06 , Vol. 22 , N. 12 , P. 3292-3303
DOI 10.1111/mec.12312
WOS© Times Cited 11
Keyword(s) adaptation, epistasis, experimental evolution, genome sequencing, parallelism
Abstract We investigated the relationship between genomic and phenotypic evolution among replicate populations of Escherichia coli evolved for 1000 generations in four different environments. By resequencing evolved genomes, we identified parallel changes in genes encoding transcription regulators within and between environments. Depending on both the environment and the altered gene, genetic parallelism at the gene level involved mutations that affected identical codons, protein domains or were widely distributed across the gene. Evolved clones were characterized by parallel phenotypic changes in their respective evolution environments but also in the three alternative environments. Phenotypic parallelism was high for clones that evolved in the same environment, even in the absence of genetic parallelism. By contrast, clones that evolved in different environments revealed a higher parallelism in correlated responses when they shared mutated genes. Altogether, this work shows that after an environmental change or the colonization of a new habitat, similar ecological performance might be expected from individuals that share mutated genes or that experienced similar past selective pressures.
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