||Harrang Estelle1, Heurtebise Serge1, Faury Nicole1, Robert Maeva1, Arzul Isabelle1, Lapegue Sylvie1
||1 : IFREMER, SG2M, LGPMM, F-17390 La Tremblade, France.
||Aquaculture (0044-8486) (Elsevier Science Bv), 2015-11 , Vol. 448 , P. 521-530
|WOS© Times Cited
||Ostrea edulis, Single Nucleotide Polymorphism, Disease resistance, Genetic and QTL mapping, Candidate genes
||The present study identifies quantitative trait loci (QTLs) in response to an experimental infection with the parasite responsible for bonamiosis, Bonamia ostreae, in two segregating families of the European flat oyster, Ostrea edulis. We first constructed a genetic-linkage map for each studied family and improved the existing genetic-linkage map for the European flat oyster with a set of SNP markers. This latter map now combines the best accuracy and the best estimate of the genome coverage available for an oyster species. Secondly, by comparing the QTLs detected in this study with those previously published for O. edulis in similar experimental conditions, we identified several potential QTLs that were identical between the different families, and also new specific QTLs. We also detected, within the confidence interval of several QTL regions, some previously predicted candidate genes differentially expressed during an infection with B. ostreae, providing new candidate genome regions which should now be studied more specifically.
|Author's final draft
||Access on demand