Holocene ocean circulation is poorly understood due to sparsity of dateable marine archives with submillennial-scale resolution. Here we present a record of mid-depth water radiocarbon contents in the Northwest (NW) Pacific Ocean over the last 12.000 years, which shows remarkable millennial-scale variations relative to changes in atmospheric radiocarbon inventory. Apparent decoupling of these variations from regional ventilation and mixing processes leads us to the suggestion that the mid-depth NW Pacific may have responded to changes in Southern Ocean overturning forced by latitudinal displacements of the southern westerly winds. By inference, a tendency of in-phase related North Atlantic and Southern Ocean overturning would argue against the development of a steady bipolar seesaw regime during the Holocene.