Contrasting effects of historical contingency on phenotypic and genomic trajectories during a two-step evolution experiment with bacteria

Type Article
Date 2016-04
Language English
Author(s) Plucain Jessica1, 2, Suau Antonia1, 2, 3, Cruveiller Stephane4, 5, 6, Medigue Claudine4, 5, 6, Schneider Dominique1, 2, Le Gac MickaelORCID1, 2, 7
Affiliation(s) 1 : Univ Grenoble Alpes, Lab Technol Ingn Med & Complex Informat Math & Ap, F-38000 Grenoble, France.
2 : CNRS, TIMC IMAG, F-38000 Grenoble, France.
3 : Conservatoire Natl Arts & Metiers, Paris, France.
4 : CEA, Direct Sci Vivant, Inst Genom, Genoscope, Evry, France.
5 : CNRS UMR8030, Evry, France.
6 : Lab Anal Bioinformat Genom & Metab, Evry, France.
7 : IFREMER, DYNECO Pelagos, F-29280 Plouzane, France.
Source Bmc Evolutionary Biology (1471-2148) (Biomed Central Ltd), 2016-04 , Vol. 16 , P. -
DOI 10.1186/s12862-016-0662-8
WOS© Times Cited 6
Keyword(s) Experimental evolution, Escherichia coli, Adaptation, Historical contingency, Epistasis
Abstract Background

The impact of historical contingency, i.e. the past evolutionary history of a population, on further adaptation is mostly unknown at both the phenotypic and genomic levels. We addressed this question using a two-step evolution experiment. First, replicate populations of Escherichia coli were propagated in four different environmental conditions for 1000 generations. Then, all replicate populations were transferred and propagated for further 1000 generations to a single new environment.
Results

Using this two-step experimental evolution strategy, we investigated, at both the phenotypic and genomic levels, whether and how adaptation in the initial historical environments impacted evolutionary trajectories in a new environment. We showed that both the growth rate and fitness of the evolved populations obtained after the second step of evolution were contingent upon past evolutionary history. In contrast however, the genes that were modified during the second step of evolution were independent from the previous history of the populations.
Conclusions

Our work suggests that historical contingency affects phenotypic adaptation to a new environment. This was however not reflected at the genomic level implying complex relationships between environmental factors and the genotype-to-phenotype map.
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How to cite 

Plucain Jessica, Suau Antonia, Cruveiller Stephane, Medigue Claudine, Schneider Dominique, Le Gac Mickael (2016). Contrasting effects of historical contingency on phenotypic and genomic trajectories during a two-step evolution experiment with bacteria. Bmc Evolutionary Biology, 16, -. Publisher's official version : https://doi.org/10.1186/s12862-016-0662-8 , Open Access version : https://archimer.ifremer.fr/doc/00333/44447/