The neodymium isotopic composition of authigenic phases of deep-sea sediment cores can be interpreted as reflecting past changes in water-mass mixing proportions if end-member water-mass compositions are constrained through time. Here we present three new records spanning 2480 to 4360 m depth in the North Atlantic Ocean that show seawater Nd isotope values in the early to mid-Holocene that are more radiogenic than values from the abyssal northwest Atlantic. This finding indicates that that the end-member composition of North Atlantic Deep Water was more stable within its core than it was at abyssal depths. The spatial distribution of the unradiogenic neodymium isotope values observed in the North Atlantic suggests a bottom source, and therefore that they were unlikely to have been due to the production of intermediate-depth Labrador Sea Water. We infer that the unradiogenic authigenic Nd isotope values were most likely derived from a pulse of poorly chemically weathered detrital material that was deposited into the Labrador Sea following Laurentide ice sheet retreat in the early Holocene. This unradiogenic sediment released neodymium into the bottom waters, yielding an unradiogenic seawater signal that was advected southward at abyssal depths and attenuated as it vertically mixed upward in the water column to shallower depths. The southward dispersion of these unradiogenic seawater values traces deep-water advection. However, the exact values observed at the most abyssal sites cannot be interpreted as proportionate to the strength of deep-water production without improved constraints on end-member changes.