Effective publicly developed adaptation strategies are crucial in managing the impacts of Climate Change. Adaptation strategy development is particularly complex in estuarine and coastal marine ecosystems because of their diverse environmental values, extensive human utilisation and the complex socio-ecological systems they support. Although many generic adaptation frameworks are available they cannot provide specific guidance for locally relevant strategy development. In contrast, situation-specific tools work well for their intended purpose but are usually unsuitable for a different situation. The gap between generic frameworks and situation-specific tools is addressed in this study by developing a set of general principles to provide guidance for the efficient and robust development of adaptation strategies. The nine principles comprise a conceptualisation of the various factors that are likely to have an effect on the success or otherwise of an adaptation strategy and they apply in any situation. An example ‘adaptation checklist’ that serves as a guide to practitioners in the field, will help ensure that all critical components are covered during the development of an adaptation strategy.