Sustained fecal-oral human-to-human transmission following a zoonotic event
Bacterial, viral and parasitic zoonotic pathogens that transmit via the fecal-oral route have a major impact on global health. However, the mechanisms underlying the emergence of such pathogens from the animal reservoir and their persistence in the human population are poorly understood. Here, we present a framework of human-to-human transmission of zoonotic pathogens that considers the factors relevant for fecal-oral human-to-human transmission route at the levels of host, pathogen, and environment. We discuss current data gaps and propose future research directions.
de Graaf Miranda, Beck Relja, Caccio Simone M., Duim Birgitta, Fraaij Pieter L. A., Le Guyader Soizick, Lecuit Marc, Le Pendu Jacques, de Wit Emmie, Schultsz Constance (2017). Sustained fecal-oral human-to-human transmission following a zoonotic event. Current Opinion In Virology. 22. 1-6. https://doi.org/10.1016/j.coviro.2016.11.001, https://archimer.ifremer.fr/doc/00358/46959/