Cold seeps frequently occur at the seafloor along continental margins. The dominant biogeochemical processes at cold seeps are the combined anaerobic oxidation of methane and sulfate reduction, which can significantly impact the global carbon and sulfur cycles. The circulation of methane-rich fluids at margins is highly variable in time and space, and assessing past seepage activity requires the use of specific geochemical markers. In this study, we report multiple sedimentary proxy records for three piston gravity cores (QDN-14A, QDN-14B, and QDN-31) from the Haima seep of the South China Sea (SCS). By combining total organic carbon (TOC), total inorganic carbon (TIC), total nitrogen (TN), total sulfur (TS), acid insoluble carbon and sulfur isotope (δ13Corganic carbon and δ34Sacid-insoluble), and δ34S values of chromium reducibility sulfur (δ34SCRS), as well as carbon isotopes of TIC (δ13CTIC) in sediments, our aim was to provide constraints on methane seepage dynamics in this area. We identified three sediment layers at about 260 – 300 cm, 380 – 420 cm and 480 – 520 cm sediment depth, characterized by particular anomalies of low δ13CTIC values and high TS content, high TS and CRS contents, and high δ34Sacid-insoluble and δ34SCRS values, respectively. On this basis, we propose that these sediment horizons correspond to distinct methane release events preserved in the sediment record. While the exact mechanisms accounting for the presence (or absence) of these particular geochemical signals in the sediment are not known, we propose that they correspond to variations in methane flux and their duration through time. Overall, our results suggest that sedimentary carbon and sulfur and their isotopes are useful tracers for better understanding of methane seepage dynamics over time.