Species-Specific Antioxidant Power and Bioactive Properties of the Extracts Obtained from Wild Mediterranean Calendula Spp. (Asteraceae)

Type Article
Date 2019-11
Language English
Author(s) Messina Concetta Maria1, Troia Angelo2, Arena Rosaria1, Manuguerra Simona1, 3, Ioannou Theodora, Curcuraci Eleonora1, Renda Giuseppe1, Hellio Claire4, Santulli Andrea1
Affiliation(s) 1 : Laboratorio di Biochimica Marina ed Ecotossicologia, Dipartimento di Scienze della terra e del Mare DiSTeM, Università degli Studi di Palermo, Via G. Barlotta 4, 91100 Trapani, Italy
2 : Dipartimento di Scienze e Tecnologie Biologiche, Chimiche e Farmaceutiche (STEBICEF), Università degli Studi di Palermo, 90123 Palermo, Italy
3 : Department of chemistry, Faculty of Science, Aristotle University of Thessaloniki, 541 24 Thessaloniki, Greece
4 : Univ Brest, CNRS, IRD, Ifremer, LEMAR, Institut Universitaire Européen de la Mer, F-29280 Plouzané, France
Source Applied Sciences-basel (2076-3417) (MDPI AG), 2019-11 , Vol. 9 , N. 21 , P. 4627 (13p.)
DOI 10.3390/app9214627
WOS© Times Cited 7
Note This article belongs to the Special Issue Antioxidants in Natural Products
Keyword(s) calendula species, marigold, supercritical fluid extraction, bioactivity, antioxidants, polyphenols
Abstract

n this study we focused on four taxa of the genus Calendula (C. maritima, C. suffruticosa subsp. fulgida, C. arvensis, and the hybrid between the first two ones), collected in Mediterranean area (Sicily). Six extracts for each species were obtained using solvents with increasing polarity (hexane, ethanol 80%, acetone 70%, and water) and through extraction by supercritical fluids (SFE). It has been observed that the solvent with the highest extraction efficiency was ethanol 80% for all species. However, SFE extracts showed high antioxidant activity comparable to the ethanol 80% extract (polyphenol, DPPH, and reducing power method). These findings were confirmed by in vitro analysis (MTT assay) where it was observed that the tested concentration (24 µg/mL), obtained from ethanol 80% and SFE extracts, showed a protective effect comparable to that induced by a synthetic antioxidant. Extraction with SFE ensured a great selectivity by avoiding the use of toxic organic solvents and thus consisted of a promising technique for sustainable production of Calendula extracts

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Messina Concetta Maria, Troia Angelo, Arena Rosaria, Manuguerra Simona, Ioannou Theodora, Curcuraci Eleonora, Renda Giuseppe, Hellio Claire, Santulli Andrea (2019). Species-Specific Antioxidant Power and Bioactive Properties of the Extracts Obtained from Wild Mediterranean Calendula Spp. (Asteraceae). Applied Sciences-basel, 9(21), 4627 (13p.). Publisher's official version : https://doi.org/10.3390/app9214627 , Open Access version : https://archimer.ifremer.fr/doc/00591/70336/