The peak of the Last Interglacial, Marine Isotope Stage (MIS) 5e (130e116 ka), provides a valuable ‘process analogue’ for validating the climatic feedbacks and forcings likely active under future anthropogenic warming. Reconstructing exact timings of MIS 5e peak warming and minimum winter sea-ice extent (WSIE) throughout the Southern Ocean (SO) will help to identify the interactions and feedbacks within the ice-ocean system. Here we present a new MIS 5e marine sediment record from the SWAtlantic sector together with 28 published core records (chronologies standardised to the LR04 d18O benthic stack; Lisiecki and Raymo, 2005) to investigate the timing and sequence of minimum WSIE and peak warming across the SO. Sea-surface temperatures (SSTs) peaked earliest in the Indian (20oEe150oE) and Atlantic (70oWe20oE) sectors, at 128.7 ± 0.8 ka and 127.4 ± 1.1 ka respectively, followed by the Pacific sector (150oEe70oW) at 124.9 ± 3.6 ka. The interval of minimum WSIE for all three sectors occurred within the period from 129e125 ka, consistent with the ~128 ka sea salt flux minimum in Antarctic ice cores. Minimum WSIE appears to have coincided with peak July insolation at 55 oS, suggesting it could be linked with the mildest winters. The reduced WSIE during MIS 5e would have likely reduced the production of deep- and bottom water masses, inhibiting storage of CO2 in the abyssal ocean and lowering nutrient availability in SO surface waters. Examining a wide spatial range of proxy records for MIS 5e is a critical step forward in understanding climatic interactions and processes that will be active under warmer global temperatures.