Here we present derived thermal-hydrological variations data during the Marine isotope stages (MISs) 10–12 using surface and subsurface dwelling planktonic foraminiferal geochemical proxies of a sedimentary core of MD05-2925 (9.3oS, 151.5oE, water depth 1661 m, core depth 1842–2430 cm), Solomon Sea. Globigerinoides ruber (s.s., white, 250–300 µm) and Pulleniatina obliquiloculata (355–425 µm) tests were hand-picked and cleaned for stable carbon and oxygen isotopes and Mg/Ca analyses. Composite benthic foraminifera tests (>250 µm, Uvigerina spp., and Bulimina spp.) are also hand-picked and cleaned for stable oxygen isotope stratigraphy. In total, 235 and 148 measurements for C-O stable isotopes and Mg/Ca ratios for planktonic foraminifera in 2–5 cm resolution for the period from 352.1 to 462.3 ka are presented in this data report, respectively. Age model is established by tuning composite benthic foraminiferal oxygen isotope to global composite benthic foraminifera oxygen isotope stack LR04. Surface and subsurface temperatures and seawater oxygen isotopes (δ18OW, without ice volume correction) were calculated.