While numerous studies have highlighted the central role of Southern Ocean (SO) dynamics in modulating rapid increases in atmospheric CO2 concentrations during deglaciations, fewer studies have yet focused on the impact of the Biological Carbon Pump - and more specifically the Carbonate Counter Pump (CCP) - in contributing to increase the CO2 concentration in oceanic surface waters and thus, in the atmosphere. Here, we present micropaleontological (coccolith, planktonic foraminifera) and geochemical (CaCO3, CaXRF, δ13CN. pachyderma) constraints from sediment core MD04-2718 retrieved in the Polar Front Zone of the Indian Ocean covering the time interval spanning Marine Isotope Stage (MIS) 12 to MIS 10 (440,000–360,000 years). We compare our results with published records from the SO to reconstruct past changes in CCP and upwelling dynamics and understand their leverage on the ocean-atmosphere portioning of CO2. We demonstrate that the sharp increase in atmospheric pCO2 during Termination V was likely associated with enhanced deep-water ventilation in the SO, that promoted the release of previously sequestered CO2 to the ocean surface as the westerly wind belt and the frontal system migrated southwards. Enhanced CCP is observed later, during MIS 11, and is likely the consequence of higher sea surface temperature and higher nutrient availability due to the reinvigoration of SO upwelling leading to increased coccolith (and to a lesser degree, planktonic foraminifera) production and export. The low eccentricity signal recorded during MIS 11 might have additionally strengthened the CCP, exerting a specific control on Gephyrocapsa morphotypes. In addition to the strong global biological productivity and higher carbon storage on land, these synergistic mechanisms may have permitted to shape the distinctive 30 ka-long pCO2 plateau characteristic of MIS 11.