Use of Human Intestinal Enteroids to Evaluate Persistence of Infectious Human Norovirus in Seawater

Type Article
Date 2022-07
Language English
Author(s) Desdouits MarionORCID1, Polo Montero David1, Le Mennec Cecile1, Strubbia Sofia1, Zeng Xi-Lei2, Ettayebi Khalil2, Atmar Robert L.2, Estes Mary K.2, Le Guyader Soizick1
Affiliation(s) 1 : Institut Franҫais de Recherche pour l’Exploitation de la Mer, Nantes, France
2 : Baylor College of Medicine, Houston, Texas, USA
Source Emerging Infectious Diseases (1080-6040) (Centers Disease Control & Prevention), 2022-07 , Vol. 28 , N. 7 , P. 1475-1479
DOI 10.3201/eid2807.220219
Abstract

Little data on the persistence of human norovirus infectivity are available to predict its transmissibility. Using human intestinal enteroids, we demonstrate that 2 human norovirus strains can remain infectious for several weeks in seawater. Such experiments can improve understanding of factors associated with norovirus survival in coastal waters and shellfish.

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Desdouits Marion, Polo Montero David, Le Mennec Cecile, Strubbia Sofia, Zeng Xi-Lei, Ettayebi Khalil, Atmar Robert L., Estes Mary K., Le Guyader Soizick (2022). Use of Human Intestinal Enteroids to Evaluate Persistence of Infectious Human Norovirus in Seawater. Emerging Infectious Diseases, 28(7), 1475-1479. Publisher's official version : https://doi.org/10.3201/eid2807.220219 , Open Access version : https://archimer.ifremer.fr/doc/00786/89824/