Fifteen species of Enixotrophon collected during expeditions of the Tropical Deep-Sea Benthos programme are reported from the Indo-West Pacific. All are illustrated using the holotypes and material collected during more than 30 years. The species were collected in the bathyal zone, living specimens occurring in depths from 198 to 1,280 m, with a majority between 250 and 800 m. One new combination, Enixotrophon pistillum (Barnard, 1959), is introduced; Trophon johannthielei Barnard, 1959 and Trophonopsis ziczac Tiba, 1981 are synonymised with E. pulchellus (Schepman, 1911). New geographical distribution data are presented for E. lochi (Marshall & Houart, 2011), E. pistillum, E. planispinus (E.A. Smith, 1906), E. plicilaminatus (Verco, 1909), E. pulchellus (Schepman, 1911) and E. sansibaricus (Thiele, 1925). Six species are recorded from the New Caledonia region, E. lochi, E. multigradus (Houart, 1990), E. obtuseliratus (Schepman, 1911), E. plicilaminatus (Verco, 1909), E. procerus (Houart, 2001) and E. pulchellus (Schepman, 1911). E. karubar n. sp. is described from Indonesia and one subadult specimen collected in the Mozambique Channel during the MAINBAZA expedition remains unidentified (Enixotrophon sp. cf. E. sansibaricus).