How to obtain an integrated picture of the molecular networks involved in adaptation to microgravity in different biological systems?

Periodically, the European Space Agency (ESA) updates scientific roadmaps in consultation with the scientific community. The ESA SciSpacE Science Community White Paper (SSCWP) 9, “Biology in Space and Analogue Environments”, focusses in 5 main topic areas, aiming to address key community-identified knowledge gaps in Space Biology. Here we present one of the identified topic areas, which is also an unanswered question of life science research in Space: “How to Obtain an Integrated Picture of the Molecular Networks Involved in Adaptation to Microgravity in Different Biological Systems?” The manuscript reports the main gaps of knowledge which have been identified by the community in the above topic area as well as the approach the community indicates to address the gaps not yet bridged. Moreover, the relevance that these research activities might have for the space exploration programs and also for application in industrial and technological fields on Earth is briefly discussed.

Full Text

FilePagesSizeAccess
Publisher's official version
51 Mo
How to cite
Willis Craig R. G., Calvaruso Marco, Angeloni Debora, Baatout Sarah, Benchoua Alexandra, Bereiter-Hahn Juergen, Bottai Daniele, Buchheim Judith-Irina, Carnero-Diaz Eugénie, Castiglioni Sara, Cavalieri Duccio, Ceccarelli Gabriele, Chouker Alexander, Cialdai Francesca, Ciofani Gianni, Coppola Giuseppe, Cusella Gabriella, Degl’innocenti Andrea, Desaphy Jean-Francois, Frippiat Jean-Pol, Gelinsky Michael, Genchi Giada, Grano Maria, Grimm Daniela, Guignandon Alain, Herranz Raúl, Hellweg Christine, Iorio Carlo Saverio, Karapantsios Thodoris, Van Loon Jack, Lulli Matteo, Maier Jeanette, Malda Jos, Mamaca Emina, Morbidelli Lucia, Osterman Andreas, Ovsianikov Aleksandr, Pampaloni Francesco, Pavezlorie Elizabeth, Pereda-Campos Veronica, Przybyla Cyrille, Rettberg Petra, Rizzo Angela Maria, Robson-Brown Kate, Rossi Leonardo, Russo Giorgio, Salvetti Alessandra, Risaliti Chiara, Santucci Daniela, Sperl Matthias, Tabury Kevin, Tavella Sara, Thielemann Christiane, Willaert Ronnie, Monici Monica, Szewczyk Nathaniel J. (2024). How to obtain an integrated picture of the molecular networks involved in adaptation to microgravity in different biological systems?. Npj Microgravity. 10 (1). 20 (5p.). https://doi.org/10.1038/s41526-024-00395-3, https://archimer.ifremer.fr/doc/00888/100025/

Copy this text