This document represents the final report of the Regional Consultation for Europe and North America on the development of Guidelines for Sustainable Aquaculture (GSA), held virtually from 27 to 29 April 2021. The objectives of the consultation were to: share current policies and practices related to aquaculture in the regions; review existing regional and national instruments for sustainable aquaculture; develop a list of priority thematic modules considering regional and national strengths and challenges; propose and prioritize possible case study concepts linked to one or more thematic modules; and identify regional priority areas to be included in the GSA.