The determination of 18 metals and metalloids was realized in 4 tissues of 62 Stenella coeruleoalba specimens stranded along the French Mediterranean coastline from 2010 to 2016. While most concentrations were comparable to mean worldwide levels, Hg levels were alarming (1190 μg g−1 dw, in average). The results were discussed together with previous measurements in the same area, from 2002 to 2009. The elements Ni and Pb (−81 % and −88 % in liver in 2010–16 compared to 2002–09), and Cd (−40 % in kidney in 2010–16 compared to 2002–09) as well as V (−79 % in liver in 2013–16 compared to 2010–12), showed promising decreasing trends, and the decrease of Zn and Cu levels below baseline values could indicate a global decreasing burden of metal contaminants. In contrary, Hg dramatically increased in dolphins since 2007 (+135 % in liver in 2010–16 compared to 2002–09), regardless of total length. On the other hand, Se levels increased only slightly since 2012, potentially not offering anymore an efficient protection against Hg, with mean Se-to-Hg molar ratios below unity in most tissues (0.26, 0.56, 1.81, and 0.57 in liver, kidney, lung and muscle, respectively).