In this article, we evaluate the performance of a commercially available lifetime-based optode and compare it with data obtained by other methods. We performed a set of 10 different tests, including targeted laboratory evaluations and field studies, covering a wide range of situations from shallow coastal waters and wastewater treatment plants to abyssal depths. Our principal conclusion is that, owing to high accuracy (+/- 2 mu M), long-term stability (more than 20 months), lack of pressure hysteresis, and limited cross-sensitivity, this method is overall more suitable for oxygen monitoring than other methods.