Sustained fecal-oral human-to-human transmission following a zoonotic event

Type Article
Date 2017-02
Language English
Author(s) de Graaf Miranda1, Beck Relja2, Caccio Simone M.3, Duim Birgitta4, 5, Fraaij Pieter L. A.1, 6, Le Guyader Soizick7, Lecuit Marc8, 9, Le Pendu Jacques10, de Wit Emmie11, Schultsz Constance12, 13
Affiliation(s) 1 : Erasmus MC, Dept Virosci, Rotterdam, Netherlands.
2 : Croatian Vet Inst, Dept Bacteriol & Parasitol, Zagreb, Croatia.
3 : Ist Super Sanita, Dept Infect Dis, Rome, Italy.
4 : Univ Utrecht, Fac Vet Med, Dept Infect Dis & Immunol, Utrecht, Netherlands.
5 : WHO Collaborating Ctr Campylobacter, Utrecht, Netherlands.
6 : Erasmus Med Ctr Sophia, Dept Pediat, Rotterdam, Netherlands.
7 : Ifremer, Microbiol Lab, Nantes, France.
8 : Inst Pasteur, INSERM U1117, Biol Infect Unit, Paris, France.
9 : Paris Descartes Univ, Necker Enfants Malades Univ Hosp, Assistance Publ Hop Paris, Necker Pasteur Ctr Infectiol,Inst Imagine, Sorbonne Paris Cite, Paris, France.
10 : Univ Nantes, CNRS, INSERM, Nantes, France.
11 : Natl Inst Hlth, Natl Inst Allergy & Infect Dis, Virol Lab, Hamilton, MT USA.
12 : Acad Med Ctr, Dept Global Hlth, Amsterdam, Netherlands.
13 : Acad Med Ctr, Dept Med Microbiol, Amsterdam, Netherlands.
Source Current Opinion In Virology (1879-6257) (Elsevier Sci Ltd), 2017-02 , Vol. 22 , P. 1-6
DOI 10.1016/j.coviro.2016.11.001
WOS© Times Cited 32
Note Emerging viruses: intraspecies transmission • Viral immunology
Abstract Bacterial, viral and parasitic zoonotic pathogens that transmit via the fecal-oral route have a major impact on global health. However, the mechanisms underlying the emergence of such pathogens from the animal reservoir and their persistence in the human population are poorly understood. Here, we present a framework of human-to-human transmission of zoonotic pathogens that considers the factors relevant for fecal-oral human-to-human transmission route at the levels of host, pathogen, and environment. We discuss current data gaps and propose future research directions.
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de Graaf Miranda, Beck Relja, Caccio Simone M., Duim Birgitta, Fraaij Pieter L. A., Le Guyader Soizick, Lecuit Marc, Le Pendu Jacques, de Wit Emmie, Schultsz Constance (2017). Sustained fecal-oral human-to-human transmission following a zoonotic event. Current Opinion In Virology, 22, 1-6. Publisher's official version : https://doi.org/10.1016/j.coviro.2016.11.001 , Open Access version : https://archimer.ifremer.fr/doc/00358/46959/